منابع مشابه
PharmGKB summary: very important pharmacogene information for RYR1.
CYP1A2 is part of the cytochrome P450 (CYP) family of drug-metabolizing enzymes. The CYP1A2 gene is found in a cluster with CYP1A1 and CYP1B1 on chromosome 15 [1]. CYP1A2 and CYP1A1 share a 5′-flanking region of approximately 23 kb, which contains shared regulatory elements, although the genes are positioned back to back and transcription occurs in opposite directions [2]. The CYP1A2 gene spans...
متن کاملPharmGKB summary: very important pharmacogene information for GSTT1.
Caroline F. Thorn(1), Yuan Ji(2), Richard M. Weinshilboum(2), Russ B. Altman(1),(3), and Teri E. Klein(1) (1)Department of Genetics, Stanford University Medical Center, Stanford, CA, USA (2)Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA (3)Department of Bioengineering, Stanford University Medical Cent...
متن کاملPharmGKB summary: very important pharmacogene information for angiotensin-converting enzyme.
Angiotensin-converting enzyme (ACE) plays an important role in two pathways which contribute to the regulation of blood pressure, the renin-angiotensin-aldosterone system (RAAS) and the kinin–kallikrien cascade (see the RAAS-acting drug pathways at PharmGKB for a simplified view of the candidate genes involved). ACE converts the inactive angiotensin I peptide (also known as Ang I or Ang 1–10) t...
متن کاملPharmGKB summary: very important pharmacogene information for G6PD.
Ellen M. McDonagha, Caroline F. Thorna, José M. Bautistac, Ilan Youngsterd, Russ B. Altmana,b, and Teri E. Kleina aDepartment of Genetics, Stanford University, California, USA bDepartment of Bioengineering, Stanford University, California, USA cDepartments of Biochemistry and Molecular Biology IV and Research Institute Hospital 12 de Octubre, Universidad Complutense de Madrid dClinical Pharmaco...
متن کاملPharmGKB summary: very important pharmacogene information for CYP3A5.
Jatinder Lambaa, Joan M. Hebertb, Erin G. Schuetzd, Teri E. Kleinb, and Russ B. Altmanc aDepartment of Experimental and Clinical Pharmacology, College of Pharmacy, Institute of Human Genetics, University of Minnesota, Minnesota bDepartment of Genetics, Stanford University, Stanford, California cDepartments of Genetics, Bioengineering, Stanford University, Stanford, California dDepartment of Pha...
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ژورنال
عنوان ژورنال: Pharmacogenetics and Genomics
سال: 2010
ISSN: 1744-6872
DOI: 10.1097/fpc.0b013e328333dae6